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Anti-SERCA2 ATPase Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | SERCA2 ATPase rabbit polyclonal antibody |
Gene Name: | Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 |
Synonyms: | SERCA2, SR Ca(2+)-ATPase 2, Calcium pump 2, Endoplasmic reticulum class 1/2 Ca(2+) ATPase, Atp2a2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse SERCA2 ATPase |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 115 kDa |
Observed MW. | 115 kDa |
Uniprot ID: | O55143, P11507 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 1000-1: 2000 | heart |
Background
ATP dependent calcium pumps are responsible, in part, for the maintenance of low cytoplasmic free calcium concentrations. The ATP pumps that reside in intracellular organelles are encoded by a family of structurally related enzymes, termed the sarcoplasmic or endoplasmic reticulum calcium (SERCA) ATPases. The SERCA1 gene is exclusively expressed in type II (fast) skeletal muscle. The SERCA2 gene is subject to tissue dependent processing which is responsible for the generation of SERCA2a muscle-specific form expressed in type I (slow) skeletal, cardiac and smooth muscle and the SERCA2b isoform expressed in all cell types.
Images
 | Western blot analysis of SERCA2 (GB112211) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
