Reactivity: | H |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | SAGA-associated factor 29 |
Synonyms: | CCDC101 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse SGF29 |
Uniprot ID: | Q9DA08 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 33 kDa / 36 kDa |
Product Usage Information
WB | Human | 1: 500-1: 1500 | MCF7 |
Background
Chromatin reader component of some histone acetyltransferase (HAT) SAGA-type complexes like the TFTC-HAT, ATAC or STAGA complexes. SGF29 specifically recognizes and binds methylated 'Lys-4' of histone H3 (H3K4me), with a preference for trimethylated form (H3K4me3). In the SAGA-type complexes, SGF29 is required to recruit complexes to H3K4me. Involved in the response to endoplasmic reticulum (ER) stress by recruiting the SAGA complex to H3K4me, thereby promoting histone H3 acetylation and cell survival.
Images
Western blot analysis of SGF29 (GB115095) at dilution of 1: 1500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |