Reactivity: | M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | SLC6A19 rabbit polyclonal antibody |
Gene Name: | Sodium-dependent neutral amino acid transporter B(0)AT1 |
Synonyms: | Solute carrier family 6 member 19, System B(0) neutral amino acid transporter AT1, Slc6a19, B0at1, Xt3 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse SLC6A19 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Uniprot ID: | Q9D687, Q2A865 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 400-1: 1000 | colon, duodenum, kidney |
Background
Transporter that mediates epithelial resorption of neutral amino acids across the apical membrane of epithelial cells in the kidney and intestine. It appears that leucine is the preferred substrate, but all large neutral non-aromatic L-amino acids bind to this transporter. Uptake of leucine is sodium-dependent. In contrast to other members of the neurotransmitter transporter family, does not appear to be chloride-dependent.
Images
Immunohistochemistry of paraffin embedded mouse colon using SLC6A19 (GB112256) at dilution of 1:900 (400x lens) | |
Immunohistochemistry of paraffin embedded mouse duodenum using SLC6A19 (GB112256) at dilution of 1:900 (400x lens) | |
Immunohistochemistry of paraffin embedded mouse kidney using SLC6A19 (GB112256) at dilution of 1:450 (400x lens) | |
Immunohistochemistry of paraffin embedded rat colon using SLC6A19 (GB112256) at dilution of 1:900 (400x lens) | |
Immunohistochemistry of paraffin embedded rat kidney using SLC6A19 (GB112256) at dilution of 1:900 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |