Reactivity: | M |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Lymphocyte-specific helicase |
Synonyms: | helicase, lymphoid, HELLS, LSH, Lymphoid specific helicase, Nbla10143, PASG, SMARCA6 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse SMARCA6 |
Uniprot ID: | Q60848 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 95 kDa / 110 kDa |
Product Usage Information
WB | Mouse | 1: 300-1: 600 | thymus |
Background
Plays an essential role in normal development and survival. Involved in regulation of the expansion or survival of lymphoid cells. Required for de novo or maintenance DNA methylation. May control silencing of the imprinted CDKN1C gene through DNA methylation. May play a role in formation and organization of heterochromatin, implying a functional role in the regulation of transcription and mitosis.
Images
Western blot analysis of HELLS (GB114967) at dilution of 1: 300 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |