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| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | SNAIL rabbit polyclonal antibody |
Gene Name: | Zinc finger protein SNAI1 |
Synonyms: | SNAI1, SLUGH2, SNA, SNAH, SNAIL, SNAIL1, dJ710H13.1, Snai1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Snai1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Cytoplasm |
Uniprot ID: | Q02085 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 800-1: 1600 | testis |
Background
Involved in induction of the epithelial to mesenchymal transition (EMT), formation and maintenance of embryonic mesoderm, growth arrest, survival and cell migration. Binds to 3 E-boxes of the E-cadherin gene promoter and to the promoters of CLDN7 and KRT8 and, in association with histone demethylase KDM1A which it recruits to the promoters, causes a decrease in dimethylated H3K4 levels and represses transcription.
Images
| Immunohistochemistry of paraffin embedded mouse testis using snail (GB11260) at dilution of 1:800 (300x lens) |
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Immunohistochemistry of paraffin embedded rat testis using snail (GB11260) at dilution of 1:800 (300x lens) |
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Immunofluorescence of paraffin embedded mouse testis using snail (GB11260) at dilution of 1:800 (300x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
