Reactivity: | H |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | SNF2H rabbit polyclonal |
Gene Name: | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 |
Synonyms: | hISWI, hSNF2H, ISWI, SMARCA5, SNF2H, WCRF135, Sucrose nonfermenting protein 2 homolog |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse SNF2H |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 122 kDa |
Observed MW. | 130 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human | 1: 300-1: 600 | HepG2, Jurkat, 293T, HEK293 |
Background
SMARCA5, also named as SNF2H or WCRF135, is a 1052 amino acid protein, which localizes in nucleus and is overexpressed in CD34-positive erythrocyte progenitor cells in acute myeloid leukemia. SMARCA5 is one of the most conserved chromatin remodeling factors. It exists in a variety of oligosubunit complexes that move DNA with respect to the histone octamer to generate regularly spaced nucleosomal arrays. Smarca5 interacts with different accessory proteins and represents a molecular motor for DNA replication, repair, and transcription.
Images
Western blot analysis of SNF2H (GB113666) at dilution of 1: 600 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |