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| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | SRC3 rabbit polyclonal antibody |
Gene Name: | Nuclear receptor coactivator 3 |
Synonyms: | NCoA-3, AIB-1, CBP-interacting protein, pCIP, RAC-3, SRC-3, ACTR, TRAM-1, Ncoa3, Aib1, Rac3, Tram1 |
Immunogen: | Recombinant protein corresponding to Mouse SRC3 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Nucleus |
Uniprot ID: | Q9Y6Q9, O09000, Q9EPU2 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1: 500-1: 3000 | brain, colon, ovary |
Background
The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation.
Images
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Immunohistochemistry of paraffin embedded mouse brain using scr3 (GB111066) at dilution of 1:1000 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse ovary using scr3 (GB111066) at dilution of 1:1000 (400x lens) |
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Immunohistochemistry of paraffin embedded rat brain using scr3 (GB111066) at dilution of 1:1000 (400x lens) |
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Immunofluorescence of paraffin embedded human colon using scr3 (GB111066) at dilution of 1:2000 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |