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Anti-STT3B Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | STT3B rabbit polyclonal |
Gene Name: | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B |
Synonyms: | Oligosaccharyl transferase subunit STT3B, STT3-B, B6dom1 antigen, Source of immunodominant MHC-associated peptides, Stt3b, Simp |
Immunogen: | Recombinant protein corresponding to Mouse STT3B |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 93 kDa |
Observed MW. | 100 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human | 1: 2000-1: 4000 | HeLa, A431, U2OS, U251, THP1 |
Background
STT3B is a component of the N-oligosaccharyl transferase (OST) enzyme which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). SST3B seems to be involved in complex substrate specificity.
Images
 | Western blot analysis of STT3B (GB112753) at dilution of 1: 2000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
