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Anti-Serine Palmitoyltransferase Rabbit pAb (100 μl)
| Reactivity: | R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Serine palmitoyltransferase 2 |
Synonyms: | KIAA0526, LCB 2, LCB2, LCB2a, Serine palmitoyltransferase 2, SPT 2, SPT2, SPTLC2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Serine Palmitoyltransferase |
Uniprot ID: | P97363 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 63 kDa / 65 kDa |
Product Usage Information
WB | Rat | 1: 300-1: 500 | colon, liver |
Background
Serine palmitoyltransferase (SPT). The heterodimer formed with LCB1/SPTLC1 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC2-SPTSSA complex shows a strong preference for C16-CoA substrate, while the SPTLC1-SPTLC2-SPTSSB complex displays a preference for C18-CoA substrate (By similarity). Plays an important role in de novo sphyngolipid biosynthesis which is crucial for adipogenesis.
Images
| Western blot analysis of Serine Palmitoyltransferase (GB114312) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
