Reactivity: | H,M |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Serum Amyloid P/SAP rabbit polyclonal antibody |
Gene Name: | Serum amyloid P-component |
Synonyms: | SAP, Apcs, Ptx2, Amyloid P component serum |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Serum Amyloid P/SAP |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 26 kDa |
Observed MW. | 24 kDa |
Uniprot ID: | P02743, P12246 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse | 1: 500-1: 1000 | liver |
Background
The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.
Images
Western blot analysis of Apcs (GB112621) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |