Reactivity: | M |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | ABCA7 rabbit polyclonal |
Gene Name: | ATP-binding cassette sub-family A member 7 |
Synonyms: | ABCA SSN, ABCA7, ABCX, Autoantigen SS N, Macrophage ABC transporter |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse ABCA7 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
IHC/IF | Mouse | 1: 1500-1: 3000 | brain |
Background
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This full transporter has been detected predominantly in myelo-lymphatic tissues with the highest expression in peripheral leukocytes, thymus, spleen, and bone marrow. The function of this protein is not yet known; however, the expression pattern suggests a role in lipid homeostasis in cells of the immune system.
Images
Immunohistochemistry analysis of paraffin-embedded mouse brain using ABCA7 (GB113271) at dilution of 1: 3000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |