Anti-ACAA2 Rabbit pAb (100 μl)

Anti-ACAA2 Rabbit pAb (100 μl)

Brand: ServiceBio
Cat. #: GB114720-100
Availability: In Stock
$259.00
-+
Reactivity: M,R    
Applications: WB    
Host Species: Rabbit    
Clonality: Polyclonal    
Gene Name:

3-ketoacyl-CoA thiolase, mitochondrial

Synonyms:

ACAA2, Acetyl CoA acyltransferase, Beta ketothiolase, DSAEC, T1

Immunogen:

KLH conjugated Synthetic peptide corresponding to Mouse ACAA2

Uniprot ID:

Q8BWT1

Isotype:

IgG

Purity:

Affinity purification

Predicted MW. / Observed MW.

42 kDa / 42 kDa




Product Usage Information

WB

Mouse, Rat

1: 1500-1: 3000

liver, kidney, lung




Background

In the production of energy from fats, this is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain unbranched 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. Also catalyzes the condensation of two acetyl-CoA molecules into acetoacetyl-CoA and could be involved in the production of ketone bodies. Also displays hydrolase activity on various fatty acyl-CoAs. Thereby, could be responsible for the production of acetate in a side reaction to beta-oxidation.




Images

Western blot analysis of ACAA2 (GB114720) at dilution of 1: 1500




Storage

Storage            Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer            PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


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