Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Short-chain specific acyl-CoA dehydrogenase, mitochondrial |
Synonyms: | ACAD3, ACADS, Butyryl CoA dehydrogenase, SCAD |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse ACADS |
Uniprot ID: | Q07417 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 45 kDa / 41 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 2000-1: 4000 | lung, kidney, colon, testis |
Background
Short-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation, an aerobic process breaking down fatty acids into acetyl-CoA and allowing the production of energy from fats. The first step of fatty acid beta-oxidation consists in the removal of one hydrogen from C-2 and C-3 of the straight-chain fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA. Among the different mitochondrial acyl-CoA dehydrogenases, short-chain specific acyl-CoA dehydrogenase acts specifically on acyl-CoAs with saturated 4 to 6 carbons long primary chains.
Images
Western blot analysis of ACADS (GB114355) at dilution of 1: 2000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |