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Anti-ACSL1 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | ACSL1 rabbit polyclonal antibody |
Gene Name: | Long-chain-fatty-acid--CoA ligase 1 |
Synonyms: | ACS1, ACSL1, Acyl CoA synthetase 1, FACL1, FACL2, LACS, LACS 1, LACS 2, LACS1, LACS2, Palmitoyl CoA ligase 1, Palmitoyl CoA ligase 2 |
Immunogen: | Recombinant protein corresponding to Mouse ACSL1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 78 kDa |
Observed MW. | 78 kDa |
Uniprot ID: | P41216 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 3000-1: 6000 | heart, kidney |
Background
ACSL1(Long-chain-fatty-acid--CoA ligase 1) is also named as FACL1, FACL2, LACS, LACS1, LACS2 and belongs to the ATP-dependent AMP-binding enzyme family. ACSL1 is a 75 kDa protein that is associated peripherally with the plasma membrane(Brian M Wiczer, etc., 2006). ACSL1 is abundantly expressed in tissues, such as liver and brown fat, that metabolize substantial amounts of triglycerides as fuel, and as such, a deficiency in ACSL1 function could have a more profound affect in those cells, resulting in hepatosteatosis and potentially increased very low density lipoprotein production by the liver or decreased thermogenic capacity in brown adipose tissue(PMID:19429676).
Images
 | Western blot analysis of ACSL1 (GB114032) at dilution of 1: 5000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
