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Anti-ADAMTS1 Rabbit pAb (100 μl)
| Reactivity: | H,M,R & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | ADAMTS1 rabbit polyclonal antibody |
Gene Name: | A disintegrin and metalloproteinase with thrombospondin motifs 1 |
Synonyms: | ADAMTS1, ADAMTS, METH1, KIAA1346, A disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif 1, ADAM metallopeptidase with thrombospondin type 1 motif 1 |
Immunogen: | Recombinant protein corresponding to Mouse ADAMTS1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Secreted |
Uniprot ID: | Q9WUQ1 |
Applications
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1:1800-1:3600 | heart, lung, testis |
Background
ADAMTS1 (a disintegrin and metalloproteinase with thrombospondin motifs 1), is the founding member of the family of secreted zinc proteases with a multidomain structure. The protein precursor consists of a signal peptide and the following domains: pro, catalytic, disintegrinlike, TS type 1 motif, cysteine rich, spacer and a variable number of thrombospondin type 1 motifs. Based on their substrate specificity, ADAMTS1 and associated family members may be key enzymes in the degradation of cartilage leading to inflammation and arthritis.
Images
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Immunohistochemistry of paraffin embedded mouse heart using ADAMTS1 (GB111350) at dilution of 1:1800 (400x lens) |
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Immunohistochemistry of paraffin embedded rat heart using ADAMTS1 (GB111350) at dilution of 1:1800 (400x lens) |
| Immunofluorescence of paraffin embedded mouse lung using ADAMTS1 (GB111350) at dilution of 1:1800 (400x lens) |
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Immunofluorescence of paraffin embedded mouse testis using ADAMTS1 (GB111350) at dilution of 1:1800 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |