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| Reactivity: | M,R & H |
| Applications: | WB & IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | AGXT rabbit polyclonal |
Gene Name: | Serine--pyruvate aminotransferase, mitochondrial |
Synonyms: | AGT, AGT1, AGXT, AGXT1, PH1, SPAT, SPT, TLH6, Alanine--glyoxylate aminotransferase |
Immunogen: | Recombinant protein corresponding to Mouse AGXT |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Mitochondrion, Peroxisome |
Predicted MW. | 46 kDa |
Observed MW. | 46 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 300-1: 600 | liver |
IHC | Human | 1: 1000-1: 2000 | liver, liver cancer |
Background
AGXT (AGT) is a key enzyme in glyoxylate detoxification. Mutations of AGXT lead to primary hyperoxaluria type I, a rare metabolic disease which is characterized by deficient AGXT, excessive hepatic oxalate production that leads to renal failure.
Images
| Western blot analysis of AGXT (GB113654) at dilution of 1: 600 |
| Immunohistochemistry analysis of paraffin-embedded human liver cancer using AGXT (GB113654) at dilution of 1: 2000 |
| Immunohistochemistry analysis of paraffin-embedded human liver using AGXT (GB113654) at dilution of 1: 2000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
