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Anti-AKAP13/p47 Rabbit pAb (100 μl)
| Reactivity: | R |
| Applications: | IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | AKAP13/p47 rabbit polyclonal |
Gene Name: | A-kinase anchor protein 13 |
Synonyms: | AKAP 13, AKAP Lbc, AKAP13, ARHGEF13, BRX, clbc, HA 3, Ht31, LBC, LBC oncogene, Lymphoid blast crisis oncogene, p47, PROTO LB, PROTO LBC |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse AKAP13/p47 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Rat | 1: 4000-1: 8000 | heart |
Background
Anchors cAMP-dependent protein kinase (PKA) and acts as an adapter protein to selectively couple G alpha-13 and Rho. Augments gene activation by the estrogen receptor in an element-specific and ligand-dependent manner. Activates estrogen receptor beta by a p38 MAPK-dependent pathway. Isoform 6 stimulates exchange activity on Rho proteins in vitro, but not on CDC42, Ras or Rac and may bind calcium ions.
Images
 | Immunohistochemistry analysis of paraffin-embedded rat heart using AKAP13 (GB113071) at dilution of 1: 8000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
