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Anti-AKAP8-like protein Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | A-kinase anchor protein 8-like |
Synonyms: | A kinase anchor protein 8 like, AKAP8 like protein, AKAP8L, AKAP95, HA95, HAP95, Helicase A binding protein 95 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse AKAP8-like protein |
Uniprot ID: | Q9R0L7 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 71 kDa / 71/95 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 1000-1: 2000 | testis, colon |
Background
Could play a role in constitutive transport element (CTE)-mediated gene expression by association with DHX9. Increases CTE-dependent nuclear unspliced mRNA export. Proposed to target PRKACA to the nucleus but does not seem to be implicated in the binding of regulatory subunit II of PKA. May be involved in nuclear envelope breakdown and chromatin condensation. May be involved in anchoring nuclear membranes to chromatin in interphase and in releasing membranes from chromating at mitosis. May regulate the initiation phase of DNA replication when associated with TMPO isoform Beta. Required for cell cycle G2/M transition and histone deacetylation during mitosis.
Images
| Western blot analysis of AKAP8L (GB114765) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
