Reactivity: | H,M |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | ANXA13 rabbit polyclonal antibody |
Gene Name: | Annexin A13 |
Synonyms: | Annexin XIII, Annexin-13, Anxa13, ANX 13, ANX A13 |
Immunogen: | Recombinant protein corresponding to Mouse ANXA13 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Uniprot ID: | P27216, Q99JG3 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse | 1: 1500-1: 3000 | colon cancer, small intestine |
Background
This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. The Annexin A13 is considered the original progenitor of the 12 members of vertebrate Annexins. The expression of Annexin A13 is highly tissue-specific, being expressed only in intestinal and kidney epithelial cells. This expression is associated with a highly differentiated intracellular transport function.It is associated with the plasma membrane of undifferentiated, proliferating endothelial cells and differentiated villus enterocytes.
Images
Immunohistochemistry of paraffin embedded human colon cancer using AnnexinA13 (GB111272) at dilution of 1:1500 (400x lens) | |
Immunohistochemistry of paraffin embedded mouse small intestine using AnnexinA13 (GB111272) at dilution of 1:1500 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |