Reactivity: | H |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Rho GTPase-activating protein 45 |
Synonyms: | HA-1, HMHA1, KIAA0223 |
Immunogen: | Recombinant protein corresponding to Mouse ARHGAP45 |
Uniprot ID: | Q3TBD2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Cell projection |
Product Usage Information
IHC/IF | Human | 1: 1000-1: 2000 | T-cell lymphoma |
Background
Contains a GTPase activator for the Rho-type GTPases (RhoGAP) domain that would be able to negatively regulate the actin cytoskeleton as well as cell spreading. However, also contains N-terminally a BAR-domin which is able to play an autoinhibitory effect on this RhoGAP activity.
Images
Immunohistochemistry analysis of paraffin embedded human T-cell lymphoma using ARHGAP45 (GB114449) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |