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Anti-ARID3A Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | AT-rich interactive domain-containing protein 3A |
Synonyms: | ARID3A, BRIGHT, Dead ringer like protein 1, DRIL1, DRIL3, DRX, E2F binding protein 1, E2FBP1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse ARID3A |
Uniprot ID: | Q62431 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Cytoplasm |
Product Usage Information
IHC/IF | Human, Mouse, Rat | 1: 400-1: 1200 | colon cancer, placenta, testis |
Background
Transcription factor involved in B-cell differentiation. Binds a VH promoter proximal site necessary for induced mu-heavy-chain transcription. Binds the minor groove of a restricted ATC sequence that is sufficient for nuclear matrix association. This sequence motif is present in matrix-associating regions (MARS) proximal to the promoter and flanking E mu. Activates E mu-driven transcription by binding these sites. May be involved in the control of cell cycle progression by the RB1/E2F1 pathway.
Images
| Immunohistochemistry analysis of paraffin embedded human placenta using ARID3A (GB114705) at dilution of 1: 400 |
| Immunohistochemistry analysis of paraffin embedded rat testis using ARID3A (GB114705) at dilution of 1: 400 |
| Immunohistochemistry analysis of paraffin embedded mouse testis using ARID3A (GB114705) at dilution of 1: 1200 |
| Immunohistochemistry analysis of paraffin embedded human colon cancer using ARID3A (GB114705) at dilution of 1: 400 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
