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| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | ATG7 rabbit polyclonal |
Gene Name: | Ubiquitin-like modifier-activating enzyme ATG7 |
Synonyms: | APG7 LIKE, APG7L, ATG7, Autophagy related protein 7, GSA7, hAGP7, ATG12-activating enzyme E1 ATG7 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human ATG7 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 78 kDa |
Observed MW. | 78 kDa |
Uniprot ID: | O95352, Q9D906, Q641Y5 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | liver, kidney |
Background
Atg7 is an E1-like enzyme that is specifically involved in autophagosome formation and is essential for autophagy. As an autophagic-related protein it is required for linking to Atg12, Atg5 and Atg8, which are essential for Atg conjugation and autophagosome formation. Atg7 has been reported as an important regulator of autophagy with starvation-induced or chemotherapeutic agent treatment. The high expression level of ATG7 is related to the survival of patients with breast cancer. There are several isoforms of ATG7 protein ranged from 68 kDa to 78 kDa.
Images
 | Western blot analysis of ATG7 (GB113752) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
