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Anti-Activin Receptor Type IA Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Activin Receptor Type IA rabbit polyclonal |
Gene Name: | Activin receptor type-1 |
Synonyms: | Activin A receptor type I, Activin A receptor type II like kinase 2, Activin receptor type-1, Activin receptor-like kinase 2, ACTR-I, ACTRI, Acvr1, ACVRLK2, FOP, TSRI, SKR1, ALK2, Hydroxyalkyl protein kinase |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Acvr1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 57 kDa |
Observed MW. | 57 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 500-1: 1500 | heart, liver |
Background
ACVR1 (activin receptor type I), also known as ALK2 or ACTRI, is a receptor for activin. It forms a stable complex with type II receptor after ligand binding. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. ACVR1 is expressed in many tissues including skeletal muscle and chondrocytes. It functions as a receptor for bone morphogenetic protein (BMP) and induces Indian hedgehog in chondrocytes during skeletal development.
Images
 | Western blot analysis of Acvr1 (GB113399) at dilution of 1: 1500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
