Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Adiponectin Receptor 2/ADIPOR2 rabbit polyclonal antibody |
Gene Name: | Adiponectin receptor protein 2 |
Synonyms: | ACDCR2, adiponectin receptor 2, Adiponectin receptor protein 2, ADIPOR1, ADIPOR2, PAQR2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Adiponectin Receptor 2/ADIPOR2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 44 kDa |
Observed MW. | 44 kDa |
Uniprot ID: | Q8BQS5 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 2000-1: 4000 | skeletal muscle, pancreas |
Background
Adiponectin is a hormone secreted by adipocytes that acts as an antidiabetic and anti-atherogenic adipokine. Two receptors for adiponectin (ADIPOR1 and ADIPOR2) have been identified. They mediate increased AMPK, MAPK and PPARA ligand activity in response to adiponectin. AdipoR1 is abundantly expressed in skeletal muscle, whereas AdipoR2 is predominantly expressed in the liver. The human ADIPOR2 gene maps to chromosome 12p13.31, and encodes a 386-amino acid protein with a molecular weight of 44 kDa. This antibody raised against 1-147aa of human AdipoR2 may cross-react with AdipoR1.
Images
Western blot analysis of ADIPOR2 (GB113921) at dilution of 1: 2000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |