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| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Bub1 rabbit polyclonal antibody |
Gene Name: | Mitotic checkpoint serine/threonine-protein kinase BUB1 |
Synonyms: | mBUB1, BUB1A, Bub1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Bub1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Uniprot ID: | O08901 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 800-1: 1600 | testis |
Background
Bub1 is an evolutionarily conserved mitotic checkpoint control protein that is present in diverse organisms including yeast and humans. The kinase functions in part by phosphorylating a member of the miotic checkpoint complex and activating the spindle checkpoint. Mutations in this gene have been associated with aneuploidy and several forms of cancer.
Images
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Immunohistochemistry of paraffin embedded mouse testis using BUB1 (GB111231) at dilution of 1:800 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |