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Anti-CC2D1A Rabbit pAb (100 μl)
| Reactivity: | H,M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | CC2D1A rabbit polyclonal antibody |
Gene Name: | Coiled-coil and C2 domain-containing protein 1A |
Synonyms: | CC2D1A, FREUD 1, Freud 1/Aki1, MRT3, Akt kinase interacting protein 1, Putative NF kappa B activating protein |
Immunogen: | Recombinant protein corresponding to Mouse CC2D1A |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 104 kDa |
Observed MW. | 130 kDa |
Uniprot ID: | Q8K1A6 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse | 1: 500-1: 1000 | brain |
Background
Transcription factor that binds specifically to the DRE (dual repressor element) and represses HTR1A gene transcription in neuronal cells. The combination of calcium and ATP specifically inactivates the binding with FRE. May play a role in the altered regulation of HTR1A associated with anxiety and major depression. Mediates HDAC-independent repression of HTR1A promoter in neuronal cell. Performs essential function in controlling functional maturation of synapses.
Images
| Western blot analysis of CC2D1A (GB114071) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
