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| Reactivity: | M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | CCR5 rabbit polyclonal |
Protein full name | C-C chemokine receptor type 5 |
Synonyms: | CC-CKR-5,CCCKR5,CCR-5,CD195,CKR-5,CKR5,CMKBR5,IDDM22,C-C motif chemokine receptor 5 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse CCR5 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 41KDa |
Observed MW. | 41KDa |
Subcellular location: | |
Uniprot ID: | P51682 |
Images
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1:500-1:1000 | Inflammatory spleen, Inflammatory liver, thymus |
IHC | Mouse, Rat | 1:500-1:1000 | lymph node |
IF | Mouse, Rat | 1:500-1:1000 | ovary, lung, inflammatory liver, immune spleen |
Background
C-C chemokine receptor type 5, also known as CCR5 or CD195, is a protein on the surface of white blood cells that is involved in the immune system as it acts as a receptor for chemokines. This is the process by which T cells are attracted to specific tissue and organ targets. Many forms of HIV, the virus that causes AIDS, initially use CCR5 to enter and infect host cells. Certain individuals carry a mutation known as CCR5-Δ32 in the CCR5 gene, protecting them against these strains of HIV.
Images
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Western blot analysis of CCR5 (GB11504) at dilution of 1:800. Line 1:Mouse Inflammatory spleen tissue lysate Line 2:Mouse Inflammatory liver tissue lysate Line 3:Mouse thymus tissue lysate Line 4:Rat Inflammatory spleen tissue lysate Line 5:Rat Inflammatory liver tissue lysate Line 6:Rat thymus tissue lysate |
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Immunohistochemistry analysis of paraffin-embedded human lymph node using CCR5 (GB11504) at dilution of 1:500 |
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Immunohistochemistry analysis of paraffin-embedded human lymph node using CCR5 (GB11504) at dilution of 1:500 |
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Immunofluorescent analysis of paraformaldehyde-fixed mouse ovary using CCR5 (GB11504) at dilution of 1:500 |
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Immunofluorescent analysis of paraformaldehyde-fixed mouse lung using CCR5 (GB11504) at dilution of 1:500 |
| Immunofluorescent analysis of paraformaldehyde-fixed mouse inflammatory liver using CCR5 (GB11504) at dilution of 1:500 |
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Immunofluorescent analysis of paraformaldehyde-fixed rat immune spleen using CCR5 (GB11504) at dilution of 1:500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
