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| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | CCR5 rabbit polyclonal antibody |
Gene Name: | C-C chemokine receptor type 5 |
Synonyms: | CC-CKR-5, CCCKR5, CCR-5, CD195, CKR-5, CKR5, CMKBR5, IDDM22, C-C motif chemokine receptor 5 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse CCR5 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Uniprot ID: | P51682, P51681, O08556 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 500-1: 1000 | lung, spleen, thymus |
Background
C-C chemokine receptor type 5, also known as CCR5 or CD195, is a protein on the surface of white blood cells that is involved in the immune system as it acts as a receptor for chemokines. This is the process by which T cells are attracted to specific tissue and organ targets. Many forms of HIV, the virus that causes AIDS, initially use CCR5 to enter and infect host cells. Certain individuals carry a mutation known as CCR5-Δ32 in the CCR5 gene, protecting them against these strains of HIV.
Images
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Immunohistochemistry of paraffin embedded mouse spleen using CCR5 (GB11505) at dilution of 1:500 (400x lens) |
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Immunohistochemistry of paraffin embedded rat spleen using CCR5 (GB11505) at dilution of 1:500 (400x lens) |
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Immunofluorescence of paraffin embedded mouse spleen using CCR5 (GB11505) at dilution of 1:500 (400x lens) |
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Immunofluorescence of paraffin embedded mouse thymus using CCR5 (GB11505) at dilution of 1:500 (400x lens) |
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Immunofluorescence of paraffin embedded rat lung using CCR5 (GB11505) at dilution of 1:500 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
