Reactivity: | H,M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Platelet endothelial cell adhesion molecule |
Synonyms: | CD31 Antigen, EndoCAM, PECAM-1, GPIIA, PECA1 |
Immunogen: | Recombinant protein corresponding to Mouse CD31 |
Uniprot ID: | Q08481 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Membrane, Cell junction |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC/IF | Human, Mouse, Rat | 1:100-1:800 | kidney, lung, ovary, Skeletal muscle, tonsil |
Background
Platelet endothelial cell adhesion molecule (PECAM-1) also known as cluster of differentiation 31 (CD31) is a protein that in humans is encoded by the PECAM1 gene found on chromosome 17. PECAM-1 plays a key role in removing aged neutrophils from the body. PECAM-1 is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions.
Images
Immunohistochemistry of paraffin embedded mouse lung using CD31 (GB11063-3) at dilution of 1:400 (400x lens) | |
Immunohistochemistry of paraffin embedded mouse ovary using CD31 (GB11063-3) at dilution of 1:400 (400x lens) | |
Immunohistochemistry of paraffin embedded mouse Skeletal muscle using CD31 (GB11063-3) at dilution of 1:400 (400x lens) | |
Immunofluorescence of paraffin embedded human tonsil using CD31 (GB11063-3) at dilution of 1:100 (400x lens) | |
Immunofluorescence of paraffin embedded mouse kidney using CD31 (GB11063-3) at dilution of 1:100 (400x lens) |
Storage
Storage | Store at -20 °C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |