Reactivity: | H |
Applications: | IHC/IF |
Host Species: | Mouse |
Clonality: | Monoclonal ) |
Gene Name: | Hematopoietic progenitor cell antigen CD34 |
Synonyms: | CD34, HPCA1, Mucosialin, Cluster designation 34, cluster of differentiation 34, CD34 antigen, CD34 molecule |
Immunogen: | Recombinant protein corresponding to Human CD34 |
Uniprot ID: | P28906 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Product Usage Information
IHC/IF | Human | 1: 500-1: 1000 | colorectal carcinoma, gastric carcinoma, liver cancer, renal carcinoma |
Background
CD34 is a 105- to 120-kDa glycophosphoprotein expressed on the majority of hematopoietic stem/progenitor cells, bone marrow stromal cells, capillary endothelial cells, embryonic fibroblasts, and some nerve tissue. CD34 is a commonly used marker for identifying human hematopoietic stem/progenitor cells and mediates cell adhesion and lymphocyte homing by binding L-selectin and E-selectin ligands. CD34 is also one of the best negative selection markers for characterizing and/or isolating human MSCs from bone marrow and other sources.
Images
Immunohistochemistry analysis of paraffin embedded human colorectal carcinoma using CD34 (GB151693) at dilution of 1: 1000 | |
Immunohistochemistry analysis of paraffin embedded human gastric carcinoma using CD34 (GB151693) at dilution of 1: 1000 | |
Immunohistochemistry analysis of paraffin embedded human liver cancer using CD34 (GB151693) at dilution of 1: 1000 | |
Immunohistochemistry analysis of paraffin embedded human renal carcinoma using CD34 (GB151693) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |