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Recombinant Anti-CD4 Rabbit mAb (100 μl)
| Reactivity: | M & M |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Monoclonal |
| Gene Name: | T-cell surface glycoprotein CD4 |
Synonyms: | CD4, CD4mut, CD4 molecule |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse CD4 |
Uniprot ID: | P06332 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Predicted MW. / Observed MW. | 55 kDa / 55 kDa |
Product Usage Information
WB | Mouse | 1: 500-1: 1000 | thymus, lymph Node, spleen |
IHC/IF | Mouse | 1: 200-1: 600 | acute lung injury, lewis lung cancer ectopic subcutaneous tumor, inflamed skin, spleen |
Background
This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
Images
| Western blot analysis of CD4 (GB15064) at dilution of 1: 500 |
| Immunohistochemistry analysis of paraffin embedded mouse lewis lung cancer ectopic subcutaneous tumor using CD4 (GB15064) at dilution of 1: 200 |
| Immunohistochemistry analysis of paraffin embedded mouse lewis lung cancer ectopic subcutaneous tumor using CD4 (GB15064) at dilution of 1: 400 |
| Immunohistochemistry analysis of paraffin embedded mouse lung from acute lung injury using CD4 (GB15064) at dilution of 1: 400 |
| Immunohistochemistry analysis of paraffin embedded mouse inflamed skin using CD4 (GB15064) at dilution of 1: 400 |
| Immunohistochemistry analysis of paraffin embedded mouse spleen using CD4 (GB15064) at dilution of 1: 200 |
| Immunohistochemistry analysis of paraffin embedded mouse spleen using CD4 (GB15064) at dilution of 1: 200 |
Storage
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
