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| Reactivity: | H |
| Applications: | IHC/IF |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | TFRC |
Protein Name: | Transferrin receptor protein 1 |
Human Gene ID: | KLH conjugated Synthetic peptide corresponding to Mouse GAPDH |
Uniprot ID: | P02786 |
Immunogen: | Synthesized peptide derived from human CD71 |
Specificity: | This antibody detects endogenous levels of CD71 |
Source: | Mouse |
Concentration: | 1 mg/ml |
Purification | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
Product Usage Information
| Applications | Species | Dilution | |
IHC/IF |
Human | 1:200-1:500 |
Background
CD71, also known as transferrin receptor protein 1 (TfR1), is a transmembrane glycoprotein composed of two disulfide-linked monomers, each of 90 kDa molecular weight. Each monomer binds one holo-transferrin molecule creating an iron-Tf-TfR complex which enters the cell by endocytosis. CD71 is present on actively proliferating cells and is essential for iron transport into proliferating cells.
Images
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Immunohistochemistry analysis of paraffin-embedded human diffuse large B-cell lymphoma using CD71(GB14029) at dilution of 1:200. |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
