Your shopping cart is empty!
Anti-CNGA1 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | CNGA1 rabbit polyclonal antibody |
Gene Name: | cGMP-gated cation channel alpha-1 |
Synonyms: | Cyclic nucleotide-gated cation channel 1, CNG channel alpha-1, CNG1, Rod photoreceptor cGMP-gated channel subunit alpha, Cncg, Cncg1, Cnga1 |
Immunogen: | Recombinant protein corresponding to Mouse CNGA1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Uniprot ID: | P29974, Q62927 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 700-1: 1400 | Skeletal muscle, spleen |
Background
Subunit of the rod cyclic GMP-gated cation channel, which is involved in the final stage of the phototransduction pathway. When light hits rod photoreceptors, cGMP concentrations decrease causing rapid closure of CNGA1/CNGB1 channels and, therefore, hyperpolarization of the membrane potential.
Images
| Immunohistochemistry of paraffin embedded mouse skeletal muscle using CNG1 (GB112590) at dilution of 1:700 (400x lens) |
| Immunohistochemistry of paraffin embedded rat skeletal muscle using CNG1 (GB112590) at dilution of 1:700 (400x lens) |
| Immunofluorescence of paraffin embedded mouse spleen using CNG1 (GB112590) at dilution of 1:700 (400x lens) |
| Immunofluorescence of paraffin embedded rat spleen using CNG1 (GB112590) at dilution of 1:700 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
