Reactivity: | H,M |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | COL6A1 rabbit polyclonal antibody |
Gene Name: | Collagen alpha-1(VI) chain |
Synonyms: | Col6a1, Alpha 1 (VI) chain (61 AA), Collagen VI, alpha 1 polypeptide, Collagen, intimal short chain collagen, Collagen, type VI, alpha 1 |
Immunogen: | Recombinant protein corresponding to Mouse COL6A1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 108 kDa |
Observed MW. | 150 kDa |
Uniprot ID: | Q04857 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 500-1: 1000 | cartilage, skin, graisse |
Background
The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The protein COL6A1 is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy.
Images
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Western blot analysis of Collagen alpha-1(Ⅵ) (GB111380) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |