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Anti-CYP27A1 Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | CYP27A1 rabbit polyclonal antibody |
Gene Name: | Sterol 26-hydroxylase, mitochondrial |
Synonyms: | CP27, CTX, CYP27, CYP27A1, Cytochrome P 450C27/25, Cytochrome P450 27, Sterol 27 hydroxylase, Vitamin D(3) 25 hydroxylase |
Immunogen: | Recombinant protein corresponding to Mouse CYP27A1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Mitochondrion |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human | 1: 1200-1: 2400 | kidney |
Background
Mitochondrial sterol 27-hydroxylase (CYP27A1) catalyzes oxidative cleavage of the sterol side chain in the bile acid biosynthetic pathway in the liver and 27-hydroxylation of cholesterol in most tissues. It belongs to the cytochrome P450 family. CYP27A1 catalyses an important sterol elimination pathway in the macrophage, and consequently may protect against atherosclerosis.
Images
 | Immunohistochemistry analysis of paraffin-embedded human kidney using CYP27A1 (GB113876) at dilution of 1: 2400 |
 | Immunofluorescent analysis of paraformaldehyde-fixed human kidney using CYP27A1 (GB113876) at dilution of 1: 2400 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |