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Anti-CYP2C9 Rabbit pAb (100 μl)
| Reactivity: | H,M,R & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Cytochrome P450 2C9 |
Synonyms: | CYP2C10, P450IIC9 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human CYP2C9 |
Uniprot ID: | P11712 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Endoplasmic reticulum, Membrane, Microsome |
Predicted MW. / Observed MW. | 56 kDa / 50 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 2000-1: 3000 | liver |
IHC/IF | Human, Mouse, Rat | 1: 800-1: 1600 | liver |
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic.
Images
| Western blot analysis of CYP2C9 (GB114267) at dilution of 1: 2000 |
| Immunohistochemistry analysis of paraffin embedded mouse liver using CYP2C9 (GB114267) at dilution of 1: 1500 |
| Immunofluorescence analysis of paraffin embedded human liver using CYP2C9 (GB114267) at dilution of 1: 800 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
