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Anti-Cardiac Troponin T Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Cardiac Troponin T rabbit polyclonal |
Gene Name: | Troponin T, cardiac muscle |
Synonyms: | TNNT2, CMD1D, CMH2, CMPD2, LVNC6, RCM3, TnTC, cTnT, troponin T2, cardiac type |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Cardiac Troponin T |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Mouse, Rat | 1: 100-1: 500 | carditis, muscle |
IF | Mouse, Rat | 1: 100-1: 500 | carditis, muscle |
Background
As part of the Troponin complex, the function of cTnT is to regulate muscle contraction. The N-terminal region of TnT that strongly binds actin most likely moves with Tm and actin during strong myosin crossbridge binding and force generation. This region is likely involved in the transduction of cooperativity down the thin filament. The C-terminal region of TnT constitutes part of the globular troponin complex domain, and participates in employing the calcium sensitivity of strong myosin crossbridge binding to the thin filament.
Images
 | Immunohistochemistry analysis of paraffin-embedded mouse carditis using CTNT (GB11364) at dilution of 1: 400 |
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Immunohistochemistry analysis of paraffin-embedded rat carditis using CTNT (GB11364) at dilution of 1: 400 |
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Immunohistochemistry analysis of paraffin-embedded rat muscle using CTNT (GB11364) at dilution of 1: 400 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
