Reactivity: | H,M,R |
Applications: | IHC |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Cytokeratin 10 rabbit polyclonal |
Gene Name: | Keratin, type I cytoskeletal 10 |
Synonyms: | 56 kDa cytokeratin, Cytokeratin-10, CK-10, Keratin-10, Krt10, K10, BCIE, BIE |
Immunogen: | Recombinant protein corresponding to Mouse Cytokeratin 10 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Human, Mouse, Rat | 1: 300-1: 600 | esophageal cancer, skin, stomach |
Background
This gene encodes a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. Mutations in this gene are associated with epidermolytic hyperkeratosis. This gene is located within a cluster of keratin family members on chromosome 17q21.
Images
Immunohistochemistry analysis of paraffin-embedded human esophageal cancer using Krt10 (GB112105) at dilution of 1: 600 | |
Immunohistochemistry analysis of paraffin-embedded human skin using Krt10 (GB112105) at dilution of 1: 600 | |
Immunohistochemistry analysis of paraffin-embedded mouse skin using Krt10 (GB112105) at dilution of 1: 600 | |
Immunohistochemistry analysis of paraffin-embedded rat skin using Krt10 (GB112105) at dilution of 1: 600 | |
Immunohistochemistry analysis of paraffin-embedded mouse stomach using Krt10 (GB112105) at dilution of 1: 600 | |
Immunohistochemistry analysis of paraffin-embedded rat stomach using Krt10 (GB112105) at dilution of 1: 600 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |