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Anti-Cytokeratin 16 / K16 Mouse mAb (100 μl)
| Reactivity: | H |
| Applications: | IHC/IF |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Keratin, type I cytoskeletal 16 |
Synonyms: | Krt16, KRT16, CK16, FNEPPK, K16, K1CP, NEPPK, PC1, keratin 16 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human CK16 |
Uniprot ID: | P08779 |
Isotype: | IgG1,κ |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Secreted, Cytoplasm |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human | 1:500-1:1000 | laryngocarcinoma, esophageal cancer, lung cancer |
Background
Keratin 16 is a type I cytokeratin. It is paired with keratin 6 in a number of epithelial tissues, including nail bed, esophagus, tongue, and hair follicles. Mutations in the gene encoding this protein are associated with the genetic skin disorders including pachyonychia congenita, non-epidermolytic palmoplantar keratoderma and unilateral palmoplantar verrucous nevus.
Images
| Immunohistochemistry analysis of paraffin embedded human laryngocarcinoma using CK16 (GB12805) at dilution of 1: 500 |
| Immunohistochemistry analysis of paraffin embedded human esophageal cancer using CK16 (GB12805) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded human lung cancer using CK16 (GB12805) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
