Reactivity: | H |
Applications: | IHC/IF |
Host Species: | Mouse |
Clonality: | Monoclonal |
Gene Name: | Cytokeratin 5/6 |
Gene ID: | 3852/3853 |
Immunogen: | Synthesized peptide derived from human Cytokeratin 5/6 |
Uniprot ID: | P13647/P02538 |
Source: | Mouse/IgG1, Kappa |
Concentration: | 1 mg/ml |
Purity: | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
Product Usage Information
IHC/IF | Human | 1: 200-1: 500 | cervical carcinoma, esophageal carcinoma |
Background
keratin 5(KRT5) Homo sapiens The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008],
Images
Immunohistochemistry analysis of paraffin embedded human cervical carcinoma using CK5/6 (GB14062) at dilution of 1: 200 |
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Immunohistochemistry analysis of paraffin embedded human esophageal carcinoma using CK5/6 (GB14062) at dilution of 1: 200 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |