Your shopping cart is empty!
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | DCC rabbit polyclonal antibody |
Gene Name: | Netrin receptor DCC |
Synonyms: | Tumor suppressor protein DCC, Dcc, CRCR1, CRC18, Colorectal cancer suppressor, Netrin receptor DCC |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse DCC |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 158 kDa |
Observed MW. | 158 kDa |
Uniprot ID: | P43146 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human | 1: 250-1: 500 | U266 |
Background
The DCC protein is a type I transmembrane glycoprotein that belongs to the immunoglobulin (Ig) superfamily. The extracellular domain is composed of four Ig like domains and six fibronectin type III repeats. Native DCC is found in three isoforms. Two forms, a long and a short isoform, are produced from the same gene but have different initiation sites. The third isoform, produced by alternative splicing, is expressed only in embryonic tissue. Mouse DCC extracellular domain shares 97% and 99% homology with human and rat DCC extracellular domains, respectively. In adults, DCC is highly expressed in the brain but is also expressed at very low levels in multiple normal tissues. In the embyro, high levels of expression are detected in the brain and neural tube.
Images
 | Western blot analysis of NetrinreceptorDCC (GB112513) at dilution of 1: 250 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
