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Anti-DCTN1/p150-glued Rabbit pAb (100 μl)
| Reactivity: | H,M,R & M,R |
| Applications: | WB & IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | DCTN1/p150-glued rabbit polyclonal |
Gene Name: | Dynactin subunit 1 |
Synonyms: | 150 kDa dynein-associated polypeptide, DAP 150, DCTN1, DP 150, Dynactin subunit 1, HMN7B, P135, p150 glued |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse DCTN1/p150-glued |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Predicted MW. | 142 kDa |
Observed MW. | 150 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 400-1: 800 | testis |
IHC | Mouse, Rat | 1: 600-1: 1200 | testis |
Background
DCTN1, also named as DAP-150, p150-glued and p135, belongs to the dynactin 150 kDa subunit family. It is required for the cytoplasmic dynein-driven retrograde movement of vesicles and organelles along microtubules. Dynein-dynactin interaction is a key component of the mechanism of axonal transport of vesicles and organelles. Defects in DCTN1 are the cause of distal hereditary motor neuronopathy type 7B (HMN7B). This antibody is specific to DCTN1.
Images
| Western blot analysis of DCTN1 (GB113083) at dilution of 1: 800 |
| Immunohistochemistry analysis of paraffin-embedded mouse testis using DCTN1 (GB113083) at dilution of 1: 1200 |
| Immunohistochemistry analysis of paraffin-embedded rat testis using DCTN1 (GB113083) at dilution of 1: 1200 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
