Reactivity: | H & H |
Applications: | WB & IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Testis-specific Y-encoded-like protein 2 |
Synonyms: | CDA1, Cell division autoantigen 1, CINAP, CTCL, DENTT, NP79, Nuclear protein of 79 kDa, TSPX, TSPYL2 |
Immunogen: | Recombinant protein corresponding to Mouse DENTT |
Uniprot ID: | Q7TQI8 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Cytoplasm |
Predicted MW. / Observed MW. | 78 kDa / 120 kDa |
Product Usage Information
WB | Human | 1: 800-1: 1200 | HeLa, 293, MCF7 |
IHC/IF | Human | 1: 300-1: 600 | esophageal carcinoma, liver cancer |
Background
Part of the CASK/TBR1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression.
Images
Western blot analysis of TSPYL2 (GB114541) at dilution of 1: 1000 | |
Immunohistochemistry analysis of paraffin embedded human esophageal carcinoma using TSPYL2 (GB114541) at dilution of 1: 300 | |
Immunohistochemistry analysis of paraffin embedded human liver cancer using TSPYL2 (GB114541) at dilution of 1: 300 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |