Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | DKK1 rabbit polyclonal antibody |
Gene Name: | Dickkopf-related protein 1 |
Synonyms: | Dickkopf-1, Dkk-1, mDkk-1, Dkk1, SK, Dickkopf homolog 1 |
Immunogen: | Recombinant protein corresponding to Mouse DKK1/KLH conjugated Synthetic peptide corresponding to Mouse DKK1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 29 kDa |
Observed MW. | 34 kDa |
Uniprot ID: | O94907, O54908 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 300-1: 800 | HeLa, HepG2, Caco2, PC-3, C2C12, PC-12, C6 |
Background
This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.
Images
Western blot analysis of DKK1 (GB112495) at dilution of 1: 300 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |