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| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Developmentally-regulated GTP-binding protein 1 |
Synonyms: | DRG-1, DRG1, NEDD-3, NEDD3 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse DRG1 |
Uniprot ID: | P32233 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 41 kDa / 41 kDa |
Product Usage Information
WB | Human | 1: 300-1: 500 | HeLa, 293T |
Background
Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP. Appears to have an intrinsic GTPase activity that is stimulated by ZC3H15/DFRP1 binding likely by increasing the affinity for the potassium ions. When hydroxylated at C-3 of 'Lys-22' by JMJD7, may bind to RNA and play a role in translation. Binds to microtubules and promotes microtubule polymerization and bundling that are required for mitotic spindle assembly during prophase to anaphase transition. GTPase activity is not necessary for these microtubule-related functions.
Images
| Western blot analysis of DRG1 (GB114278) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
