Your shopping cart is empty!
Anti-DTYMK Rabbit pAb (100 μl)
| Reactivity: | M & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | DTYMK rabbit polyclonal antibody |
Gene Name: | Thymidylate kinase |
Synonyms: | dTMP kinase, Dtymk, Tmk, CDC8, TMPK |
Immunogen: | Recombinant protein corresponding to Mouse DTYMK |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Cytoplasm |
Predicted MW. | 24 kDa |
Observed MW. | 24 kDa |
Uniprot ID: | P97930 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse | 1: 500-1: 1000 | kidney, brain |
IHC/IF | Human, Mouse, Rat | 1: 200-1: 1800 | bladder, bladder cancer, colon cancer, kidney |
Background
DTYMK is a 212 amino acid protein that belongs to the thymidylate kinase family and is involved in pyrimidine metabolism. Specifically, DTYMK catalyzes the ATP-dependent conversion of dTMP (deoxythymidine monophosphate) to dTDP (deoxythymidine diphosphate), which then functions as one of the four nucleotides in DNA. Via its role in the catalytic creation of dTDP, DTYMK plays an important role in the pathway of DNA synthesis and is thought to be involved in cell cycle progression and cell growth. DTYMK expression levels peak during the S phase (synthesis phase) of the cell cycle, further supporting the role of DTYMK in DNA synthesis.
Images
| Western blot analysis of Dtymk (GB112644) at dilution of 1: 500 |
 | Immunohistochemistry of paraffin embedded mouse kidney using Dtymk (GB112644) at dilution of 1: 1800 (400x lens) |
 | Immunohistochemistry of paraffin embedded rat kidney using Dtymk (GB112644) at dilution of 1: 1800 (400x lens) |
 | Immunofluorescence of paraffin embedded human bladder cancer using Dtymk (GB112644) at dilution of 1: 650 (400x lens) |
 | Immunofluorescence of paraffin embedded human colon cancer using Dtymk (GB112644) at dilution of 1: 650 (400x lens) |
| Immunofluorescence of paraffin embedded mouse bladder using Dtymk (GB112644) at dilution of 1: 650 (400x lens) |
| Immunofluorescence of paraffin embedded rat bladder using Dtymk (GB112644) at dilution of 1: 650 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
