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Recombinant Anti-Doublecortin Mouse mAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Neuronal migration protein doublecortin |
Synonyms: | DBCN, Dbct, DC, DCX, Doublecortex, Doublin, Lis-X, Lissencephalin X, SCLH, XLIS |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse DCX |
Uniprot ID: | O88809 |
Isotype: | IgG1 |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 41 kDa / 41 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 1000-1: 2000 | lung(new born), fetal brain |
Background
Microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCLK1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May participate along with PAFAH1B1/LIS-1 in a distinct overlapping signaling pathway that promotes neuronal migration.
Images
| WB analysis of DCX(GB15317). Sample: Protein treated by RIPA Lysis Buffer (G2002). Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h. Primary antibody: 1: 2000, 4°C overnight. Secondary antibody: HRP conjugated Goat Anti-Mouse lgG (H+L) (GB23301), 1: 3000, RT, 1h. |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
