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Anti-Dynamin 2 Rabbit pAb (100 μl)
| Reactivity: | H & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Dynamin-2 |
Synonyms: | CMTDI1, CMTDIB, DI CMTB, DNM2, DYN2, dynamin 2, DYNII |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Dynamin 2 |
Uniprot ID: | P39054 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Cytoskeleton |
Predicted MW. / Observed MW. | 98 kDa / 100 kDa |
Product Usage Information
WB | Human | 1: 300-1: 600 | HeLa, K562, 293 |
IHC/IF | Human, Mouse, Rat | 1: 300-1: 900 | colon, kidney, pancreas, stomach |
Background
Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones . Plays an important role in vesicular trafficking processes, in particular endocytosis. Involved in cytokinesis . Regulates maturation of apoptotic cell corpse-containing phagosomes by recruiting PIK3C3 to the phagosome membrane .
Images
| Western blot analysis of DNM2 (GB114607) at dilution of 1: 600 |
| Immunohistochemistry of paraffin embedded human colon using DNM2 (GB114607) at dilution of 1: 300 |
| Immunohistochemistry of paraffin embedded mouse kidney using DNM2 (GB114607) at dilution of 1: 300 |
| Immunohistochemistry of paraffin embedded rat pancreas using DNM2 (GB114607) at dilution of 1: 300 |
| Immunohistochemistry of paraffin embedded human stomach using DNM2 (GB114607) at dilution of 1: 300 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
