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Anti-EDEM2 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | ER degradation-enhancing alpha-mannosidase-like protein 2 |
Synonyms: | C20orf31, C20orf49 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse EDEM2 |
Uniprot ID: | Q8BJT9 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 65 kDa / 65 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 1000-1: 3000 | blood |
Background
Involved in the endoplasmic reticulum-associated degradation (ERAD) pathway that targets misfolded glycoproteins for degradation in an N-glycan-dependent manner . May initiate ERAD by promoting the first mannose trimming step of ERAD substrates, from Man9GlcNAc2 to Man8GlcNAc2 (By similarity). Seems to recognize and bind to exposed hydrophobic regions in target proteins .
Images
| Western blot analysis of EDEM2 (GB115242) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
