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Anti-EIF2D Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Eukaryotic translation initiation factor 2D |
Synonyms: | HCA56, LGTN, ligatin |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse EIF2D |
Uniprot ID: | Q61211 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm |
Product Usage Information
IHC/IF | Mouse, Rat | 1: 800-1: 2400 | liver, kidney |
Background
Translation initiation factor that is able to deliver tRNA to the P-site of the eukaryotic ribosome in a GTP-independent manner. The binding of Met-tRNA(I) occurs after the AUG codon finds its position in the P-site of 40S ribosomes, the situation that takes place during initiation complex formation on some specific RNAs. Its activity in tRNA binding with 40S subunits does not require the presence of the aminoacyl moiety. Possesses the unique ability to deliver non-Met (elongator) tRNAs into the P-site of the 40S subunit. In addition to its role in initiation, can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits.
Images
| Immunohistochemistry analysis of paraffin embedded rat liver using LGTN (GB114973) at dilution of 1: 800 |
| Immunohistochemistry analysis of paraffin embedded mouse kidney using LGTN (GB114973) at dilution of 1: 800 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
